There are a few things in Tau-44 that can take you out if you're not paying attention or afk while cruising from one point to another.
There is the nebula right beside Singapore which is a highly explosive gas zone and most small crafts need to avoid the gas pouches. It's a natural minefield so to say. Then, you have two suns with overlapping corona. if you don't know how to fly past them, you can take damage too.
And last one, there is this highly radioactive sector that does a lot of damage if you don't know it's limits.