It's a great idea. I'd love for a stack of completely empty (No bases / little to NPCs).
This would tie in well with my idea of getting a model for an Ageira jump ship. At last we could RP expanding the Gate/Lane Network, rather than being stuck repairing Trade Lanes (which gets repetitive) and building at sites where progress never seems to occur.
Actually, this idea works brilliantly with 4.86's Player-owned stations. If we could build our own stations in these empty systems, we could have true player diplomacy, dynamic borders and supply-demand based trading.
The only catch is, don't go putting silly things like the Privas Cluster in, and it will be fine.