Hmm, the Razer gamepad looks a lot like my Belkin Nostromo T52e, which I absolutely adore. My keyboard is almost strictly for chat. The T52 has three modes, so you get a lot of options.
OTOH, I have a RAT7 mouse I *really* like. If these guys have a gamepad as good, I may have to consider switching.
EDIT: The T52 requires nothing but it's driver - it translates button presses to keystrokes. I'm assuming the Razer is similar.