Sorry if I repeated things that had already been said in my post, but I wanted to point out that I have the same opinion and I couldn't be bothered to read half the thread when everyone goes "no u can't!!!" or "all fine!!!".
The main problem is - well, let me start this way: I love RP trading. What does that mean? I pick a base that is most fitting for the faction, ship and character I fly. For example: Planetform. I would start at Methyr-Tydfill and take Fluorine. Now I look - where does it go? Then I check - what is sold there, what can I take from there? I try to pick the most fitting freight - not always possible, but hey, a good transport pilot never flies empty. But I try to pick short routes if the freight is not too fitting. (I never take human freight though, if it's not a passenger transportation ship.) Going by that I also always think about what a base should buy or should sell. And when I end up at a planet, with only alcohol to take from it, I feel a bit stupid. As if something went horribly wrong there. - So, I don't fly a pre-planned route, but plan my route while going, two to three bases ahead. And I love to vary my routes. Not just Methyr-Tydfill -> California Minor -> ... -> MT. I like to go around. Many bases somehow don't get involved in routes that way. They are just not worth going to because they don't buy or sell anything good to take with you. Some have way too much stuff (-> rare metals) and some have just weird stuff.