i have Mailwarebytes too but i use Avast next to it,since my old m8 recommended i Never use it as a main force against virus's.
but if you have no important files a hardrive wipe may be a viable option.
and this is comming from the guy who found out in 2012 he had over 3100 virus's and 200+trojans on my old computer... RIP crappy 5 year old hardrive :'(