I dont have to worry about artifact smugglers in 100. They go between omicron delta and alaska, they never pass through our guard system. The cardamine smugglers DO, and so I consider them a larger threat than any of the players running artifacts through.
Alien organisms are not contraband, they're used for terraforming and are harmless to people. It's not something any lawful organization has to worry about. Nomad equipment and nomad brains -are- considered contraband by the order when carried by anyone who doesnt have reason to carry them.
EDIT:
And while you're correct that alaska isnt a guard system, liberty lawfuls in that system are well within their boundaries to openly fire on anyone passing through that space who isnt cleared to be there. Hell, they can blast anyone even approaching the minefield in new york just for looking too closely - guard system or not, they make the rules.
Likewise, the order makes the rules when it comes to omicron minor and omicron 100. If we dont want you there, or think you're a threat to our operations, you're dead.