As the rules are written the first player to engage cruise for whatever reason is fleeing. Regardless of the direction he's cruising in.
Kane, not hoodlum, stated that it does not matter how you flee, via tradelanes cruising or thrusters or in fact swimming, you have fled, but only once you are out of scanner range. Take that as gospel.
However if you fly 10k away from a fight only to turn round and re-engage, I would consider that re-engagement. At the moment the fleeing and re-engagement rules need some work to make them clear. They are being looked at.
Frankly use common sense, if someone is far too far from a fight to be considered still in, then he should be considered fleeing. However if they got that far via thrusters do not engage cruise to catch up as you become the one that is fleeing, by any interpretation of the rules.
Saint Del is considered a holy healer of diseases of children, but also as a protector of cattle.