First of all, I am a excessive weapon group user. It is essential for dogfights, to have instant access to the various groups (shield busters/hull breakers/SNAC).
But I discovered a very annoying thing: After I dock and undock, my weapon groups are sometimes scrambled or mixed. So I might have the weapon group one doubled and no weapon group on button two.
That is really strange and killed me more then one time, yet. Imagine you are in a battle and recognize, that you can't switch quickly.