I'll admit I used to powertrade the slaves->cardie run earlier in my time on the server, but now that I've got a decent bank account I find myself floating around carrying goods with the intent of stirring up roleplay rather than for profit.
My usual route now consists of Basic Alloys, Superconductors, Consumer Goods, Neon, Boron, Robotic Components, Optronics and whatever other garbage I get my hands on from New York and ferry the whole mixed-bag of goodies up to Malta. They seem to have an over abundance of labour and are very welcoming of a supplies transport such as the Alsatia.
I then buy Food, Water and Oxygen on Malta which is taken to Freeport 10. I then buy Niobium there for a trip to either London or Manhattan depending on the mood.
I developed my roleplay distinctly around not doing the powertrade run. No slaves because I'm a good girl and no cardie because Misaka doesn't like it.