Mudd, once again you amaze me. Great idea, but as others said would be hard to implement. Cardi=faster turn speed and weapons are more accurate, however when it wears off you turn much more slowly, weapons are much less accurate. Weed=ship shakes less when shot, when it wears off, you need to have food rations (not synth paste mind you) and water in your cargo hold or you suffer a huge penalty to turn rate.
Just an idea. But as someone said, would need to be lawful variants too. Hard to implement, but a great bonus for RP.