I've actually found that the most dangerous part about NPC's is that they will ram into you. Or that you dodge into a meteor. Otherwise, their blasters don't do anything to you (my Hammerhead) and even if they did it wont be for long. Sometimes they really suprise you though; whatever you do, don't jump into a Jumphole without knowing there wont be a billion Molly's that kill your awesome ship full (FULL. 70.) of lane hackers (Londonberry!). Yeah, that'd be bad.