I'd say we make missions 5x more profitable. That sounds about right. That would mean that it would not be uncommon to get one offering 1 mill, which would actually make missions USEFUL. Right now, their only real use is for rep.
I believe that the Zoner vs. Nomad missions were brought up once before. Sounds like a great Idea to me, and same goes for the Order vs. Nomads one. I REALLY don't understand why the Order doesn't offer those. Oh, and the Isis needs more missions. Badly. You can only get one at a time, and that's very, very, very annoying if you need to fail missions to lower your Order rep or do missions to increase it.