The minefields will kill you most of the time, unless you have a fully kitted up VHF and then you can usually get away with flying though them.
Though don't trust the auto-pilot and don't try flying through minefields or explosive gas pockets during lag, you'll be dead and the first sign you'll get that your in trouble will be your ship blowing up.
Except the zone 21 minefield, that will kill BS's off easily.
Even fully out-fitted ones, so (unless your planning a suicide trip or know exactly where the gap is to get to the alaska JG), I strongly recommend you don't go near it.
So depending on what level your shield is and what ship your flying either:-