Disruption missiles can be avoided. Although I don't play much now, I did some time ago. Increased cruise speed gives you even more advantage than in Vanilla.
Basically it's a skill on when you should launch your CMs. Might take up to 30-40 of them to avoid one group of fighters. But it is possible to escape in any situation, not dependent on how many enemies are chasing you.
This of course might change as I'm intended to give the most advanced enemies (Corsairs flying Titan, Outcasts flying Sabre) advanced versions of cruise disruptor. But all other enemies remain with normal CD.